PEPTIDES FOR GUT HEALTH
Peptides for gut Health
The health of our gut is closely linked to many diseases, including digestive, metabolic and autoimmune. Changes in composition of our gut bacteria, damage to the gut lining and inflammation are all contributory factors. At From Within we provide access to holistic options such as innovative peptides like KPV, BPC-157, Larazotide, Thymosin Alpha 1 and LL-37 which have profound benefits in the microbiome.
KPV
KPV, a naturally occurring peptide found in the body, particularly in the hormone alpha-melanocyte-stimulating hormone (α-MSH), is composed of three amino acids: lysine, proline and valine. It has been shown to have several potential health benefits such as:
– Anti-Inflammatory properties– KPV may help reduce inflammation by inhibiting the production of inflammatory cytokines.
– Immune Modulation– helps regulate the immune system and improve immune function
– Anti-microbial effects– alternative to antibiotics for skin conditions like severe acne, eczema & psoriasis
KPV is currently being investigated as a potential treatment for a variety of conditions, including inflammatory bowel disease, psoriasis, and acne. It can be administered through different routes, such as orally, topically, or intravenously. However, more research is needed to fully understand its safety and efficacy
BPC-157
BPC-157 otherwise knowns as “body protective compound” is a 15 amino acid peptide found in human gastric juice. Well known among athletes for its powerful anti-inflammatory properties that aid in recovery, it is also has several potential benefits including:
– Gastrointestinal protection:It may protect the stomach and intestines from ulcers and inflammation.
– Wound healing:It may accelerate wound healing and promote tissue regeneration.
– Anti-inflammatory effects:promoting the repair of damaged intestinal lining, reducing inflammation, and supporting a balanced gut microbiome
BPC 157 stimulates the production of growth factors and promotes the formation of new blood vessels, which aids in the healing of damaged gut tissue. Studies suggest that BPC 157 can help repair the intestinal barrier, potentially reducing the symptoms of leaky gut syndrome. By promoting gut health, BPC 157 may contribute to a more balanced gut microbiome.
Larazotide
Larazotide acetate, a” Zonulin blocker”, is a single-chain eight-amino acid peptide that is believed to act as a tight junction regulator, capable of restoring intestinal barrier function.
Zonulin is a protein that acts as a key regulator of tight junctions between intestinal epithelial cells, essentially controlling the permeability of the gut barrier. When zonulin levels increase, it can disrupt tight junctions, leading to a “leaky gut” where larger molecules can pass through the intestinal lining, potentially triggering immune responses.
Primary benefits include blocking zonulin in order to repair intestinal permeability, an instigating factor in health conditions like autoimmunity, allergy, asthma, eczema & autism spectrum disorders.
Thymosin alpha 1
Thymosin alpha 1 is a 28 amino acid peptide naturally occurring in the thymus gland that has long been recognized for modifying, enhancing, and restoring immune function. TA1 lowers inflammatory cytokines and helps in development of T-cells & B cells.
Key benefits include:
– T cell development – Thymosin stimulates the production of T cells, which help defend the body from pathogens like viruses, bacteria, and fungi.
– B cell development –Thymosin helps B cells develop into plasma cells, which produce antibodies.
– Inflammation – Thymosin beta-4 (Tβ4) can reduce levels of inflammatory cytokines, such as TNF-α.
– Neuroprotection – Thymosin has shown neuroprotective effects in models of stroke, traumatic brain injury, and EAE demyelinatio
Due to its powerful benefits in immune function, it can be very supportive for anyone dealing with conditions like SIBO, other inflammatory digestive conditions or going through heavy metal detoxification.
LL-37
LL-37 is a 37 amino acid peptide produced by epithelial cells and immune cells, such as neutrophils and macrophages. It is found in various tissues and body fluids, including the skin, lungs, gastrointestinal tract, and blood. plays an important role in the innate immune system, defending the body against infections. It also has potential therapeutic applications in treating bacterial infections, wound healing, and inflammatory diseases.
Potential benefits in the gut include:
– Maintains gut lining: LL-37 helps maintain the integrity of the colon mucosal barrier, which is made up of epithelial and immune cells.
– Balances gut microbiome: LL-37 helps maintain a healthy balance of beneficial bacteria in the gut.
– Prevents leaky gut syndrome: LL-37 helps prevent leaky gut syndrome by supporting the integrity of the gut lining.
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